Chlorothiazide should be used cautiously in patients with renal disease resulting in severe renal impairment because the drug decreases the glomerular. Easy to read FDA package insert, drug facts, dosage and administration, and adverse effects for Diuril (Chlorothiazide). Chlorothiazide sodium for injection, USP is a diuretic and a vial containing: Chlorothiazide sodium equiva- . toxicity. Refer to the package insert for lithium.

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Moderate Proton pump inhibitors have been associated with hypomagnesemia. Moderate Additive hypotensive effects may occur when nitroprusside is used concomitantly with other antihypertensive agents.

Vial stoppers do not contain natural rubber latex. Since pentamidine may cause QT prolongation independently of electrolyte imbalances, the risk for cardiac arrhythmias is potentiated by the concomitant use of agents associated with electrolyte loss.

Thiazides should be discontinued before carrying out tests for parathyroid function. Moderate Patients receiving a diuretic during treatment with venlafaxine may be at greater risk of developing syndrome of inappropriate antidiuretic hormone secretion SIADH. Moderate Sulfonamides may cause photosensitization and may increase the photosensitizing effects of thiazide diuretics. In those men with significant corpora cavernosa venous leakage, hypotension might be more likely. After oral use diuresis begins within 2 hours, peaks in about 4 hours and lasts about 6 to 12 hours.

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Moderate Both thiazide diuretics and carbamazepine are associated with hyponatremia. Finally, both thiazides and sulfonylureas have been reported to cause photosensitivity reactions; concomitant use may increase the risk of photosensitivity. Send the page ” ” to a friend, relative, colleague or yourself. NSAIDS have been associated with an inhibition of prostaglandin synthesis, which may result in reduced renal blood flow leading to renal insufficiency and increases in blood pressure that are often accompanied by peripheral edema and weight gain.


Moderate There is potential for additive hypotensive effects when conivaptan is coadministered with antihypertensive agents. Moderate Concomitant use of antihypertensive agents with levodopa can result in additive hypotensive effects. Heart failure guidelines recommend adding a thiazide diuretic to standard therapy for hypertensive patients with reduced ejection fraction heart failure HFrEF and mild fluid retention.

Measure potassium concentrations at baseline and periodically during dichlorphenamide treatment. Moderate Hyponatremia has been reported very rarely during mirtazapine administration.

If progressive renal impairment becomes evident, consider withholding or discontinuing diuretic therapy. The risk of QT prolongation from ziprasidone is increased in the presence of hypokalemia or hypomagnesemia. Major The manufacturer warns that the coadministration of dolasetron with diuretics associated with hypokalemia could increase the risk of QT prolongation. Until further data are available, thiazide diuretics should be used with caution in patients with sulfonamide hypersensitivity.

Serum calcium concentrations were similar before and during treatment.

Potassium levels should be within the normal range prior to and during therapy with ondansetron. Major Patients receiving antihypertensive agents should be closely monitored during amifostine infusions due to additive effects.


Do not use, thiazide diuretics generally not effective in ciuril setting. If isoproterenol is used concomitantly with antihypertensives, the blood pressure should be monitored as the administration of isoproterenol can compromise the effectiveness of antihypertensive agents.

Patients should diuirl advised to inform their prescriber of their use of CoQ Do not give by subcutaneous or intramuscular injection. According to the OBRA guidelines, antihypertensive regimens should be individualized to achieve the desired outcome while minimizing adverse effects.

Moderate Coadministration of thiazide diuretics and antineoplastic agents such as methotrexate may result in reduced renal excretion of the antineoplastic agent and therefore increased myelosuppressive effects. When chronically administered, diuretics decrease peripheral vascular resistance. Hydrocodone; Potassium Guaiacolsulfonate; Pseudoephedrine: Moderate Patients with hyponatremia or hypovolemia are more susceptible to developing reversible renal insufficiency when given angiotensin converting enzyme ACE inhibitors and diuretics concomitantly.


Moderate Patients receiving a diuretic during treatment with paroxetine may be at greater risk of developing syndrome of inappropriate antidiuretic hormone secretion SIADH.

In general, use diuretics with caution in patients with hepatic disease since minor alterations of fluid and electrolyte balance may precipitate hepatic diuri.

Visually inspect parenteral products for inseet matter and discoloration prior to administration. In general, patients with a documented sulfonamide allergy are considered to be predisposed for development of allergic drug reactions. Risk versus benefit should be addressed in patients receiving diuretics and solifenacin.

Moderate A manufacturer of topical tretinoin states that tretinoin, ATRA should be administered with caution in patients who are also taking drugs known to be photosensitizers, such as thiazide diuretics, as concomitant use may augment phototoxicity. Thiazides may decrease urinary calcium excretion.

Diuril Oral Suspension mg/5mL, 8 oz. Bottle

When medication can be taken orally, the equivalent dosage of chlorothiazide tablets or oral suspension may be substituted for IV therapy. Major Dose adjustment of vitamin D analogs may be necessary during coadministration with thiazide diuretics. Pre-existing hypokalemia and hyperuricemia can also be potentiated by packabe anhydrase inhibitors. Major Thiazide diuretics may cause the urine to become alkaline.

Thiazide diuretics, such as chlorothiazide, have been reported to activate or exacerbate systemic lupus erythematosus SLE. Orthostatic hypotension may occur during treatment with thiazide diuretics.