27 set. trofoblástica gestacional; dois relataram mola hidatiforme completa, dois às evoluções da doença trofoblástica gestacional, cinco artigos. (2)Rio de Janeiro Trophoblastic Disease Center, Associação Brasileira de Doença Trofoblástica Gestacional, Rio de Janeiro, RJ, Brazil. RESUMO Doença trofoblástica gestacional inclui um grupo interrelacionado de doenças originadas do tecido placentário, com tendências distintas de invasão.

Author: Mikaktilar Durisar
Country: Tajikistan
Language: English (Spanish)
Genre: Relationship
Published (Last): 9 July 2016
Pages: 193
PDF File Size: 11.30 Mb
ePub File Size: 19.69 Mb
ISBN: 119-5-34647-705-9
Downloads: 60744
Price: Free* [*Free Regsitration Required]
Uploader: Totaur

Human chorionic gonadotropin and associated molecules. Although of limited clinical significance, micrometastases can be seen scattered diffusely throughout the lung parenchyma.

Shortened duration of human chorionic gonadotrophin surveillance following complete or partial hydatidiform mole: The image is improved by contrast administration 2,20, Services on Demand Journal. On T2-weighted images, a hyperintense mass can be seen in the parametrial tissue, whereas vaginal involvement presents as a bulging into the fornix with a hyperintense signal and ill-defined borders Such lesions rarely form cavities Figure 8.

Residual lung lesions after completion of chemotherapy for gestational trophoblastic neoplasia: Complete hydatidiform mole originates from the fertilization of an oocyte without maternal chromosomes by a haploid sperm with subsequent duplication of paternal DNA, giving rise to an egg of exclusively parthenogenetic origin, with a diploid 46,XX karyotype. Human chorionic gonadotropin follow-up in patients with molar pregnancy: The diagnosis of molar pregnancy by MR imaging of the placenta: After being trofoblaatica, patients with GTD should be evaluated at a referral center for its treatment, where trofoblaetica uterine contents can be evacuated by vacuum aspiration 1,2.

Doenca Trofoblastica Gestacional

Angiography in GTN Conventional angiography can be used for the embolization of vaginal and liver metastases. Am J Obstet Gynecol. Hemorrhagic complications of gestational trophoblastic disease. Such signs and symptoms include anemia, hyperemesis gravidarum, hyperthyroidism, respiratory failure, and preeclampsia Anechoic spaces within the mass are related to hemorrhage, tissue necrosis, cysts, or vascular spaces 2, Gestational trophoblastic disease II: Gadolinium contrast-enhanced MRI scan of the pelvis, showing, hypointense lesions with avid uptake and vascular dilation in the myometrium, sometimes in close contact with the uterine effusion, in patients treated for GTN.


Mola hidatiforme e doença trofoblastica gestacional

Partial hydatidiform mole results from the fertilization of a normal egg by two sperm, resulting in a zygote with a egstacional 69,XXY or 69,XXX diandric karyotype Expert Rev Mol Diagn. Many vessels are visualized in all MRI scans. Traditionally, such patients have undergone gestaciona, and ligation of the uterine arteries, making subsequent reproduction impossible 2, Accepted after revision September 9, Note the absence of embryonic tissue and its attachments. MRI scan at 27 weeks of pregnancy, showing a fetus without morphological anomalies and two distinct placental areas: Patients should not attempt to conceive avoided during this period.

Transvaginal ultrasound showing an empty endometrial cavity, adjacent to egstacional large quantity of amorphous, anechoic, multivesicular material, suggesting tubal molar pregnancy, which was subsequently confirmed by histopathology. In the past, it was common for patients with molar pregnancy to present with marked symptoms: It is known that a low PI indicates a higher number of arteriovenous communications and greater neovascularization. However, the imaging findings are nonspecific and can be difficult to distinguish from those of, for example, retained products of conception or an ectopic pregnancy with GTN The typical image is that of dense nodules with well-defined contours, usually multiple and bilateral Figure 7.

Persistent trophoblast disease following partial molar pregnancy. Sonographic and Doppler imaging in the diagnosis and treatment of gestational trophoblastic disease: At some facilities, despite the superiority of transvaginal imaging, pre-chemotherapy molar pregnancy patients often do not undergo transvaginal ultrasound due to the chance that a vaginal metastasis, which has trlfoblastica risk of major bleeding 2will be encountered. Royal College of Obstetricians and Gynaecologists; [cited Nov 12].


MOLA HIDATIFORME. – ppt video online carregar

Curr Probl Diagn Radiol. The volume of the uterine lesion must be determined because it has an established relationship with the size of the tumor and the risk of chemoresistance The role of repeat uterine evacuation in Treatment of GTN The treatment of GTN essentially consists of chemotherapy, for which the histopathological diagnosis is not a prerequisite 1, Metastases derived from choriocarcinoma are characteristically hypervascular, with a tendency to bleed 2.

Choriocarcinoma is a rarer type that often generates distant metastases. In the brain, there are typically multiple lesions, primarily trofobblastica in the parietal lobe at the junction between the white and gray matter. bestacional

Influence of oral contraceptives in the development Int J Gynaecol Obstet. Maternal and perinatal outcomes of first pregnancy after chemotherapy for gestational trophoblastic neoplasia in Brazilian women. Int J Gynecol Cancer.

Surgery and radiotherapy are necessary in some patients with high-risk GTN, especially in those with chemoresistance. Etiopathogenesis of hydatidiform mole Hydatidiform mole constitutes an error of fertilization.

Utility of commonly doema commercial human chorionic gonadotropin immunoassays in the diagnosis and management of trophoblastic diseases. In such cases, it is common to identify an embryo, or even a fetus, that is malformed and has anomalous attachments. Pathology doeena gestational trophoblastic diseases. Low risk of relapse after achieving undetectable HCG levels in women with complete molar pregnancy. Because it has a lower risk of uterine perforation, vacuum aspiration is preferable to curettage.

Lindholm H, Flam F.