These bidirectional differences are not captured in a traditional equianalgesic table.,; Dose-dependent conversions: The conversion ratio of. Opiate Equianalgesic Dosing Chart. Pharmacy & Therapeutics Committee. Note: Published tables vary in the suggest algesic to morphine. Clinical response is. TABLE 1: OPIOID EQUIANALGESIC TABLE. NB: It is important to recognize the limitations of opioid equianalgesic tables. Equianalgesic doses have been.

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Because equianalgesic tables are inherently inaccurate, dose titration to optimal effect is essential. Tolerancesensitizationcross-tolerancemetabolismand hyperalgesia may be complex factors in some individuals. Equianalgesic conversions used in this calculator are based on the American Pain Society guidelines and critical review papers regarding equianalgesic dosing. Contact the Pain Service for other alternatives.

An equianalgesic or opioid chart is a conversion chart that lists equivalent doses of analgesics drugs used to relieve pain.

Dihydroetorphine DHE is one of the strongest analgesic opioid alkaloids known; it is to 12, times more potent than morphine. Opioid conversions in acute equianalgezic. Methadone is different from most opioids considering its potency can vary depending on how long it is taken.


Values for the potencies represent opioids taken orally unless another route of administration is provided. American Society of Health-System Pharmacists. Some patients request to be switched to a different narcotic due to stigma associated with a particular drug e. Views Read Edit View history. Appropriate monitoring is required.

Pentazocine lactate IV [14]. Home Academy Blog About. The equianalgesic chart indicates that 1. Use of this table for conversion from fentanyl to other opioids can overestimate the dose of the new agent and may result in an overdosage.


The mean terminal plasma elimination half-lives of racemic tramadol and racemic M1 are 6. In patients receiving long-acting opioid formulations SRtransdermala “rescue” dose for breakthrough pain is recommended.

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Chary are general guidelines. National Institute of Health. Interactions with other drugsfood and drinkand other factors may increase or decrease the effect of certain analgesics and alter their half-life. Opioid Analgesics These are general guidelines. Practice guidelines for transdermal opioids in malignant pain.


Doses listed are equivalent to 10 mg of parenteral morphine. Methadone acute [17] [18].

Opioid Equianalgesic Doses

Lower doses should be used initially, then titrated up to achieve pain relief. As stated above, because equianalgesic tables are inherently inaccurate, the availability of breakthrough doses is paramount. Oral hour morphine equivalent. American Pain Society; Meclofenamic acid Mefenamic acid.

Equianalgesic Chart (Changes in italics)

Continue looking for other causes of sedation and respiratory depression. These variables are rarely included in equianalgesic charts. A Guide for Effective Dosing. Incomplete cross-tolerance is a reduction in equianalgesic dose when changing from one opioid to another.