This resource may include information that has not been approved by the US Food and Drug Administration. For full prescribing information, including. Fosphenytoin official prescribing information for healthcare professionals. Includes: indications, dosage, adverse reactions, pharmacology and more. Medscape – Epilepsy dosing for Cerebyx (fosphenytoin), frequency-based adverse contraindications, pregnancy & lactation schedules, and cost information. be expressed as phenytoin sodium equivalents (PE) when prescribing; There is.

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Dapoxetine The metabolism of Fosphenytoin can be decreased when combined with Dapoxetine. Chlorhexadol The risk or severity of adverse effects can be increased when Fosphenytoin is combined with Chlorhexadol. Mefenamic acid The metabolism of Fosphenytoin can be decreased when combined with Mefenamic acid. Iproclozide The risk or severity of adverse effects can be increased when Fosphenytoin is combined with Iproclozide.

Fosphenytoin

Hyperglycemia, resulting from the inhibitory effect of phenytoin the active metabolite of Fosphenytoin Sodium Injection on insulin release, has been reported. Parenteral phenytoin affects ventricular automaticity. Dexlansoprazole The metabolism of Fosphenytoin can be decreased when combined with Dexlansoprazole. Diphenadione The metabolism of Diphenadione can be increased when combined with Fosphenytoin. Atomoxetine The metabolism of Fosphenytoin can be decreased when combined with Atomoxetine.

The clearance of phenytoin the active prescriving of Fosphenytoin Sodium Injection is decreased slightly in elderly patients and lower or less frequent dosing may be required [see Clinical Pharmacology Clozapine The metabolism of Fosphenytoin can be increased when combined with Clozapine. The pharmacokinetics of phenytoin following IV administration of Pro-Epanutin, are complex and when used in an emergency setting e.

For Dose reduction in patients with Renal or Hepatic impairment, please see guidance towards the end of this section. Estramustine The metabolism of Fosphenytoin can be decreased when combined with Estramustine. Captopril The metabolism of Captopril can be increased when combined with Fosphenytoin.

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Fosphenytoin – FDA prescribing information, side effects and uses

Ethoxzolamide The risk or severity of osteomalacia can be increased when Ethoxzolamide is combined with Fosphenytoin. Cefradine The metabolism of Fosphenytoin can be increased when combined with Cefradine. Linagliptin The metabolism of Fosphenytoin can be decreased when combined with Linagliptin. Fish oil The metabolism of Fosphenytoin can be decreased when combined with Fish oil. Dezocine The risk or severity of adverse effects can be increased when Dezocine is combined with Fosphenytoin.

The pharmacokinetics and protein binding of fosphenytoin, phenytoin, and diazepam were not altered when diazepam and CEREBYX were concurrently administered in single submaximal doses. Dirithromycin The fosphenytoih of Fosphenytoin can be decreased when combined with Dirithromycin. The IM route should be considered for adult patients when there is not an urgent need to control seizures.

Pro-Epanutin Concentrate for Infusion / Solution for Injection

Administration of phenytoin to pregnant animals resulted in an increased incidence of fetal malformations and other manifestations of developmental toxicity including embryofetal death, growth impairment, and behavioral abnormalities in multiple species at clinically relevant doses [see Data ].

Doxazosin The metabolism of Fosphenytoin can be decreased when combined with Doxazosin. Cholecalciferol The metabolism of Fosphenytoin can be decreased when combined with Cholecalciferol. Granisetron The metabolism of Fosphenytoin can be decreased when combined with Granisetron. Danoprevir The metabolism of Fosphenytoin can be decreased when combined with Danoprevir.

Mebicar The risk or severity of adverse effects can be increased when Fosphenytoin is combined with Mebicar. Malformations such as orofacial clefts, cardiac defects, dysmorphic facial features, nail and digit hypoplasia, and growth abnormalities including microcephaly have been reported among children born to women with epilepsy who took phenytoin during pregnancy.

Metyrosine Fosphenytoin may increase the sedative activities of Metyrosine. Abemaciclib The metabolism of Fosphenytoin can be decreased when combined with Abemaciclib. Ethyl loflazepate The serum concentration of Fosphenytoin can be increased when it is combined with Ethyl loflazepate.

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Haloperidol The metabolism of Fosphenytoin can be decreased when combined with Haloperidol. For fosphenttoin control of generalized convulsive status epilepticus and prevention and treatment of seizures occurring during neurosurgery.

It is important to note that early manifestations of hypersensitivity, such as fever or lymphadenopathy, may be present even though rash is not evident. Date of revision of the text. Infusion tolerance was evaluated in clinical studies.

Concurrent adverse events or clinical infirmation change suggesting an allergic process were not seen [see Warnings and Precautions 5. Estradiol acetate The metabolism of Fosphenytoin can be increased when combined with Estradiol acetate.

In women of childbearing potential Pro-Epanutin should not be used in women of childbearing potential unless other antiepileptic drugs are ineffective or not tolerated and when possible, the woman is made aware of the risk of potential harm to the foetus and the importance of planning pregnancy. The most significant drug interactions following administration of CEREBYX are expected to occur with niformation that interact with phenytoin.

Methdilazine The therapeutic efficacy of Fosphenytoin can be decreased when used in combination with Methdilazine. Digitoxin The metabolism of Digitoxin can be increased when combined with Fosphenytoin. Ethosuximide The serum concentration of Fosphenytoin can be increased when it is combined with Ethosuximide.

Carbutamide The metabolism of Fosphenytoin can be decreased when combined with Carbutamide. Volume mL to draw up.