Oral Surg Oral Med Oral Pathol. Sep;60(3) Lichenoid dysplasia: a distinct histopathologic entity. Krutchkoff DJ, Eisenberg E. We have observed. Citation. M Virdi, A Sachdev, A Gupta, K Aggarwal. Lichen Planus Or Lichenoid Dysplasia: Is It Premalignant!. The Internet Journal of Head and Neck Surgery. We have observed, both in the literature and in practice, that pathologists frequently fail to appreciate subtle dysplastic features in lesions with lichenoid.
|Published (Last):||12 May 2009|
|PDF File Size:||16.61 Mb|
|ePub File Size:||19.8 Mb|
|Price:||Free* [*Free Regsitration Required]|
Pathology and genetics head and neck tumours.
Oral lichenoid lesions related to dental restorative materials. Find articles by Kumud Mittal. Normal epithelium was obtained from patients undergoing extraction for impacted third lihenoid with no sign of inflammation or any other pathology.
Increased nuclear-cytoplasmic ratio was also the most frequently encountered disorder in epithelial dysplasia, together with cell and nucleus pleomorphism, seen in Conclusion This case was clinically diagnosed as lichen planus but was confirmed to be LD histologically.
Interobserver and intraobserver variability in the histologic assessment of oral lichen planus. Cells that were clumped together or not clear were not taken into consideration. Moreover morphometric studies may help to distinguish benign from potentially premalignant lichen planus 7.
Lichenoid Dysplasia–A Case Report with a Review of Differential Diagnosis
J Oral Med ; Lichfnoid clinical study of patients with oral lichen planus in China. Crit Rev Oral Biol Med ; 13 5: Is Oral Lichen Planus Premalignant?
The oral lichen planus cases were reassessed by three independent examiners, fysplasia the histopathology criteria set by Eisenberg1 3 Table 1 to confirm initial diagnosis.
After 63, 32, and 56 mean 50 months, dysplasla developed in all three. Recent studies are changing the Idea that oral lichen planus and lichenoid dysplasia should be seen as two completely separate entities. Classification of Oral Lichenoid Lesions. Today it is known that alterations to the normal epithelial cell maturation pattern are strongly correlated to lesions evolving malignantly.
Lichenoid dysplasia: a distinct histopathologic entity.
On the other hand, they also suggest that cell and nucleus pleomorphism is a highly relevant finding, as it points to lichenoid dysplasia and consequently patients that require closer clinical follow-up. Furthermore, relevance of Histochemical markers as prognostic licehnoid in predicting the premalignant behavior of OLP needs more studies.
Edwards PC, Kelsch R. The implication of this premise is that patients dysplaaia lichenoid dysplasia represent a risk group, which can be identified by the appropriate use of available diagnostic methods and, as such, can be distinguished from patients with OLP with no dysplasia-related increased risk of development of oral cancer 3.
Although it is sysplasia common, oral lichen planus is fraught with controversy, mainly in relation to the possibility of it becoming a malignant condition. Nuclear Area, A C: Comparison of Spinous cell maximum diameter in OLP, normal mucosa and oral carcinoma.
Open in a separate window.
Oral lichenoid dysplasia: a clinicopathologic analysis.
It does not imply dysplastic changes in lichen planus. Close Enter the site. After lichfnoid years of periodic follow up and postsurgical excision, no sign of recurrence was observed.
Diagnosis and management of oral lichenoid reactions. The separation between the two is of utmost importance as each of them has their own prognosis and treatment plan. Rajendran R, Sivapathasundharam B. Notwithstanding the controversy that surrounds this topic, health care workers must be fully aware of the importance of providing close follow-up to patients with lichen planus and other chronic diseases.
The oral lesions of Lichen planus. Photomicrograph showing an area of transformation of saw tooth shaped rete ridges into drop shaped rete ridges black arrows H and E, 40X. Lee and Fabiger; Therefore, it is lichenoid dysplasia – and not lichen planus – that should be categorized as a condition that may evolve to malignancy.
Related articles Erythema multiforme graft versus host disease lichenoid drug reactions oral lichenoid dysplasia oral lichenoid lesion oral lichen planus stomatitis venenata.
Oral cavity is commonly affected by number of lichenoid lesions, whose clinical and histopathologic features overlap due to the presence of inflammatory cells in connective tissue.